Je Suis Nul en Orthographe by Jean-Michel Oullion

By Jean-Michel Oullion

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Pneumoniae and other Grampositive bacteria. Such understanding may lead to the development of new antibacterial therapeutic agents. S. pneumoniae is the most common cause of fatal pneumonia in the elderly, and it is one of the most common causes of middle ear infections and meningitis in children. The present vaccine consists of a mixture of 23 different capsular polysaccharides. While this vaccine is very effective in young adults, it is only about 60 percent effective in the elderly. In children less than 2 years of age the vaccine is ineffective and is not recommended due to the inability of this age group to mount an antibody response to the penumococcal polysaccharides.

Author(s): Straetemans M, Sanders EA, Veenhoven RH, Schilder AG, Damoiseaux RA, Zielhuis GA. Source: The Pediatric Infectious Disease Journal. 2003 June; 22(6): 515-24. Review. cmd=Retrieve&db=PubMed&list_ uids=12799508&dopt=Abstract • Risk factors for the development of otitis media. Author(s): Dhooge IJ. Source: Curr Allergy Asthma Rep. 2003 July; 3(4): 321-5. Review. cmd=Retrieve&db=PubMed&list_ uids=12791209&dopt=Abstract • Role of respiratory viruses in children with acute otitis media. Author(s): Monobe H, Ishibashi T, Nomura Y, Shinogami M, Yano J.

These aims are designed to delineate the initial interaction, adherence, and colonization which represents the first in a series of steps that culminates in otitis media. These studies may suggest avenues for blocking interaction of Spn with host cells either by immunization or direct intervention blockade with isolated receptor moieties or bacterial adhesin components. ; Microbiology; University of Alabama at Birmingham Uab Station Birmingham, Al 35294 Timing: Fiscal Year 2001; Project Start 01-JAN-1999; Project End 08-MAY-2001 Summary: The objective of this research proposal is to develop a better understanding of the structural properties and mechanism of action of S.

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